DPP4 anticorps

N° du produit ABIN452285

L’anticorps Souris Monoclonal anti-DPP4 a été validé pour FACS. Il convient pour détecter DPP4 dans des échantillons de Humain.

Aperçu rapide pour DPP4 anticorps (ABIN452285)

Antigène: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DPP4 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: BA5b

Détail du produit anti-DPP4 anticorps

Specificité: The antibody recognizes CD26, a 110 kDa type II membrane glycoprotein, which is a peptidase expressed on mature thymocytes, T cells (especially activated), B cells, NK cells and macrophages.

Réactivité croisée (Details): Species reactivity (tested):Human

Attributs du produit: Synonyms: ADCP2, Dipeptidyl peptidase 4, DPP IV, Dipeptidyl peptidase IV, ADABP, TP103, T-cellactivation antigen CD26, Adenosine deaminase complexing protein 2

Purification: Protein A affinity chromatography

Pureté: > 95 % by SDS-PAGE

Immunogène: A human T cell clone

Isotype: IgG2a

Information d'application

Indications d'application: Flow cytometry: 1.5 μg/mL. Positive control: human peripheral blood leukocytes.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur DPP4

Antigène: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Autre désignation: CD26 / DPP4

Sujet: CD26, also known as dipeptidyl peptidase IV (DPP-IV), is a homodimeric cell surface serine peptidase that degradates IFN-gamma-induced cytokines, acts as a T cell costimulatory molecule, and participates in multiple immunopathological roles in leukocyte homing and inflammation. Alterations in its peptidase activity are characteristic of malignant transformation. The enzymatic activity increases dramatically with tumour grade and severity. CD26 is expressed in various blood cell types, but also e.g. in cells that are histogenetically related to activated fibroblasts. Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.Synonyms: ADABP, ADCP2, Adenosine deaminase complexing protein 2, DPP IV, Dipeptidyl peptidase 4, Dipeptidyl peptidase IV, T-cell activation antigen CD26, TP103

ID gène: 1803

UniProt: P27487

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity